2025 Course Schedule
Critical Issues in Tumor Microenvironment: Angiogenesis, Metastasis and Immunology
In Person Meeting Schedule
All sessions for this course will be held at the Starr Center in Boston, MA USA.
Monday, November 10, 2025
| 9:00 A.M. | Check-in/Registration, Continental Breakfast |
| 10:00 A.M. | Opening Remarks Rakesh K. Jain, PhD |
| 10:10 A.M. | Tumor Microenvironment I: Angiogenesis and Vascular Function Rakesh K. Jain, PhD |
| 11:20 A.M. | Q&A Moderator: Dai Fukumura, MD, PhD |
| 11:35 A.M. | Break (15 minutes) |
| 11:50 A.M. | Tumor Microenvironment II: Vascular Normalization and Immunotherapy Rakesh K. Jain, PhD |
| 1:10 P.M. | Q&A Moderator: Dai Fukumura, MD, PhD |
| 1:25 P.M. | Lunch Break – Boxed lunches provided |
| 2:25 P.M. | Tumor Microenvironment III: Extracellular Matrix, Lymphatics and Metastasis Rakesh K. Jain, PhD |
| 3:45 P.M. | Q&A Moderator: Lance Munn, PhD |
| 4:00 P.M. | Break (30 minutes) |
| 4:30 P.M. | Cancer Immunology and Immunotherapy Overview Arlene Sharpe, MD, PhD |
| 5:35 P.M. | Q&A Moderator: Zohreh Amoozgar, PhD |
Tuesday, November 11, 2025
| 9:00 A.M. | Continental Breakfast |
| 10:00 A.M. | Circadian Clock and Metabolic Vulnerabilities of Cancer Chi Van Dang, MD, PhD |
| 11:05 A.M. | Q&A Moderator: Melin Khandekar, MD, PhD |
| 11:20 A.M. | Break (30 minutes) |
| 11:50 A.M. | Skull Bone Marrow as a Site for Immuno-Surveillance of Healthy Brain and Brain Tumors Jonathan Kipnis, PhD |
| 12:55 P.M. | Q&A Moderator: Marc Charabati, PhD |
| 1:10 P.M. | Lunch Break – on your own |
| 2:10 P.M. | Determinants of How Tumors Use Metabolism to Support Growth Matthew G. Vander Heiden, MD, PhD |
| 3:15 P.M. | Q&A Moderator: Sonu Subudhi, MD, PhD |
| 3:30 P.M. | Break (30 minutes) |
| 4:00 P.M. | Using Cell Transfer to Remodel the Tumor Microenvironment Carl June, MD (virtual, live Q&A) |
| 5:05 P.M. | Q&A Moderator: Vassia Salameti, PhD |
Wednesday, November 12, 2025
| 9:00 A.M. | Continental Breakfast |
| 10:00 A.M. | AI in Basic and Clinical Oncology Eliezer Van Allen, MD |
| 11:05 A.M. | Q&A Moderator: Sonu Subudhi, MD, PhD |
| 11:20 A.M. | Break (30 minutes) |
| 11:50 A.M. | Microbiota: a Key Orchestrator of Cancer Therapy Giorgio Trinchieri, MD |
| 12:55 P.M. | Q&A Moderator: Benjamin Wolf, MD, PhD |
| 1:10 P.M. | Lunch Break – on your own |
| 2:10 P.M. | Identifying Immune Vulnerabilities in Solid Tumors Lisa M. Coussens, PhD |
| 3:15 P.M. | Q&A Moderator: Timothy Padera, PhD |
| 3:30 P.M. | Break (30 minutes) |
| 4:00 P.M. | RREBELLIOUS INTERFERENCE: Challenging old paradigms and discovering new strategies for targeting pediatric brain tumors Robert Wechsler-Reya, PhD |
| 5:05 P.M. | Q&A Moderator: Taylor Uccello, PhD |
Thursday, November 13, 2025
| 9:00 A.M. | Continental Breakfast |
| 10:00 A.M. | Dissecting the Ecosystem of Gliomas by Single-Cell and Spatial Genomics Mario L. Suva, MD, PhD |
| 11:05 A.M. | Q&A Moderator: Sonu Subudhi, MD, PhD |
| 11:20 A.M. | Break (30 minutes) |
| 11:50 A.M. | Mechanisms of Malignant Progression Robert A. Weinberg, PhD |
| 12:55 P.M. | Q&A Moderator: Lei Xu, PhD |
| 1:10 P.M. | Lunch Break – on your own |
| 2:10 P.M. | Fibroblast Heterogeneity in Solid Tumors: Implications for Pancreatic Cancer David A. Tuveson, MD, PhD |
| 3:15 P.M. | Q&A Moderator: Heena Kumra, PhD |
| 3:30 P.M. | Break (30 minutes) |
| 4:00 P.M. | Neural Influences on Primary and Metastatic Brain Tumors Frank Winkler, PhD |
| 5:05 P.M. | Q&A Moderator: Taylor Uccello, PhD |
| 5:20 P.M. | Summary and Closing Remarks Rakesh K. Jain, PhD |
Friday, November 14, 2025
| 9:00 A.M. | Continental Breakfast & Poster Set Up |
| 10:00 A.M. | Lessons from the Clinic: Novel Diagnostics and Therapeutic Outcomes George Sledge, MD |
| 11:05 A.M. | Q&A Moderator: Zohreh Amoozgar, PhD |
| 11:20 A.M. | Break (30 minutes) |
| 11:50 A.M. | Emerging Strategies to Improve CAR-T Cell Therapy for Glioblastoma and Other Solid Tumors Hideho Okada, MD, PhD |
| 12:55 P.M. | Q&A Moderator: Vassia Salameti, PhD |
| 1:10 P.M. | Lunch Break – Boxed lunches provided |
| 2:10 P.M. | Poster Session |
| 3:10 P.M. | Poster Award Presentation |
| 3:30 P.M. | Career Round Table Discussion (Academia • Industry • Law) |
| 5:00 P.M. | Networking Reception |
